Characterization of Patients with Non-Alcoholic fatty Liver Disease in a Highly Complex Colombian Hospital in 2013
DOI:
https://doi.org/10.22516/25007440.421Keywords:
Fatty liver, insulin resistance, obesityAbstract
Non-alcoholic fatty liver disease (NAFLD) affects 2% to 8% of the general population. It is associated with obesity, type 2 diabetes, metabolic syndrome and insulin resistance.
Objective: The objective of this study was to characterize patients with NAFLD who were treated in the Hepatology Department of a 4th level hospital between 2006 and 2011.
Methods: This was a descriptive, observational and retrospective study of a population consisting of all patients treated in the hepatology department of a 4th level hospital who had been diagnosed with NAFLD. Patients with other liver diseases were excluded. Data was collected from medical records on a form designed by the researchers. Data were then tabulated and analyzed in SPSS ® version 17.0. Measures of central tendency, position and dispersion were calculated for quantitative variables, and absolute and relative frequencies were calculated for qualitative variables. The Mann-Whitney U test and the and chi-square test were used as appropriate.
Results: 58.5% of the sample were female patients. We found that 52.3% of the sample were overweight according to BMI, and 72.1% were diagnosed with fatty liver by ultrasound.
Conclusion: We found that most patients with NASH have elevated body mass indices similar to reports published elsewhere.
Downloads
References
Souza MR, Diniz M de F, Medeiros-Filho JE, Araújo MS. Metabolic syndrome and risk factors for non-alcoholic fatty liver disease. Arq Gastroenterol 2012; 49(1): 89-96.
Bhat G, Baba CS, Pandey A, Kumari N, Choudhuri G. Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease. World J Hepatol 2012; 4(7): 209-17.
Bellentani S, Marino M. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann Hepatol 2009; 8(Suppl. 1): S4-8.
Santos LF, Hernández G, Varón A, Beltrán O, Botero RC, Mejía G. Enfermedad hepática por infiltración grasa no alcohólica: La nueva pandemia del milenio. Rev Col Gastroenterol 2010; 25(4): 380-398.
Roldan-Valadez E, Favila R, Martínez-López M, Uribe M, Méndez-Sánchez N. Imaging techniques for assessing hepatic fat content in nonalcoholic fatty liver disease. Ann Hepatol 2008; 7(3): 212-20.
Farrell GC, van Rooyen D, Gan L, Chitturi S. NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. Gut Liver 2012; 149-71.
Leite AB, Mattos AA, Mattos AZ, Coral GP, Evaldt S. Risk factors for nonalcoholicsteatohepatitis in cryptogenic cirrhosis. Arq Gastroenterol 2012; 49(4): 245-9.
Cubides VI, Guevara LG. Enfermedad hepática grasa no alcohólica: NAFLD. Rev Col de Gastroenterol 2004; 19(1): 44-49.
Jun DW. [The role of diet in non-alcoholic fatty liver disease]. Korean J Gastroenterol 2013; 61(5): 243-51.
Centis E, Moscatiello S, Bugianesi E, Bellentani S, Fracanzani AL, Calugi S. Stage of change and motivation to healthier lifestyle in non-alcoholic fatty liver disease. J Hepatol 2013; 58(4): 771-7.
Idrovo V, Guevara G. Enfermedad hepática grasa no alcohólica: NAFLD. Rev Colomb Gastroenterol 2004; 19 (1): 44-9.
Lam B, Younossi ZM. Treatment options for nonalcoholic fatty liver disease. Therap Adv Gastroenterol 2010; 3(2): 121-137.
Farell GC, George J, Hall P, McCullough AJ. Fatty Liver Disease: NASH and Related Disorders. NEJM 2005; 353(20): 2200-2201.
Suzuki A, Angulo P, Lymp J, St Sauver J, Muto A, Okada T, Lindor K. Chronological development of elevated aminotransferases in a nonalcoholic population. Hepatology 2005; 41(1): 64-71.
Angulo P. Nonalcoholic Fatty Liver Disease. N Engl J Med 2002; 346(16): 1221-31.
Ortiz-Lopez C, Lomonaco R, Orsak B, Finch J, Chang Z, Kochunov VG, Hardies J, Cusi K. Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). Diabetes Care 2012; 35(4): 873-8.
Hashimoto E, Taniai M, Tokushige K. Characteristics and diagnosis of NAFLD/NASH. J Gastroenterol Hepatol 2013; 28 (Suppl. 4): 64-70.
Downloads
Published
How to Cite
Issue
Section
License
Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes:
Los autores/as ceden sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Licencia de reconocimiento de Creative Commons que permite a terceros compartir la obra siempre que se indique su autor y su primera publicación en esta revista.
Los contenidos están protegidos bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
