Necrotizing pancreatitis due to Ascaris lumbricoides: Causes, diagnosis, and current treatment

Authors

DOI:

https://doi.org/10.22516/25007440.671

Keywords:

Ascaris lumbricoides, Necrotizing pancreatitis

Abstract

Necrosis in acute pancreatitis presents a high mortality rate despite advances in critical care. After biliary and alcoholic etiology, the third most common cause of pancreatitis is idiopathic etiology, with 10% of cases related to parasites, being Ascaris the most common parasite involved in pancreas necrosis and inflammation. Considering the high rates of mortality related to necrotizing pancreatitis, a case of ascariasis is analyzed, including its growing epidemiology, its causes, its clinical and imaging diagnosis, and its antiparasitic treatment based on current evidence.   

Downloads

Download data is not yet available.

Author Biographies

Silvia Carolina Barbosa-Valenzuela, Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

Maite Nieto , Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

Daniela Ramirez, Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

José Ariza, Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

Wilmar Montañez, Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

Laura Alvarado, Fundación Cardioinfantil

Departamento de gastroenterología. Bogotá, Colombia.

References

Pérez F, Arauz E. Pancreatitis aguda: artículo de revisión. Rev Med Cient. 2020;33(1):64-85. https://doi.org/10.37416/rmc.v33i1.570

Rawla P, Bandaru SS, Vellipuram AR. Review of Infectious Etiology of Acute Pancreatitis. Gastroenterology Res. 2017;10(3):153-158. https://doi.org/10.14740/gr858w

Pipiková J, Papajová I, Šoltys J, Schusterová I. Occurrence of the most common helminth infections among children in the Eastern Slovak Republic. Public Health. 2017;150:71-76. https://doi.org/10.1016/j.puhe.2017.05.011

Khuroo MS, Rather AA, Khuroo NS, Khuroo MS. Hepatobiliary and pancreatic ascariasis. World J Gastroenterol. 2016;22(33):7507-17. https://doi.org/10.3748/wjg.v22.i33.7507

Claus PE, Ceuppens AS, Cool M, Alliet G. Ascaris lumbricoides: challenges in diagnosis, treatment and prevention strategies in a European refugee camp. Acta Clin Belg. 2018;73(6):431-434. https://doi.org/10.1080/17843286.2018.1436956

Plan para enfermedades tropicales desatendidas. [Internet] Ginebra: Organización Mundial de la Salud; 2006 [consultado el 15 de septiembre de 2020]. Disponible: https://www.who.int/mediacentre/news/releases/2006/pr60/es/index1.html

Al-Tameemi K, Kabakli R. Ascaris lumbricoides: Epidemiology, diagnosis, treatment, and control. Asian J Pharm Clin Res. 2020;13(4):8-11. https://doi.org/10.22159/ajpcr.2020.v13i4.36930

Klimovskij M, Dulskas A, Kraulyte Z, Mikalauskas S. Ascariasis of the pancreatic duct. BMJ Case Rep. 2015;2015:bcr2014207936. https://doi.org/10.1136/bcr-2014-207936

Polanía-Liscano HA, Jiménez-Sánchez HC, Polanía-Galindo DJ. Ultrasonografía endoscópica para el diagnóstico de áscaris biliar: reporte de caso y revisión de la literatura. Rev Colomb Gastroenterol. 2020;35(4):537-541. https://doi.org/10.22516/25007440.410

Macedo C, Almeida N, Ferreria AM, Figueiredo P. Ascariasis as an unexpected cause of obstructive jaundice with ascending cholangitis in an urban area. RPDI. 2019;15(2):83-86.

Leppäniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, Ball CG, Parry N, Sartelli M, Wolbrink D, van Goor H, Baiocchi G, Ansaloni L, Biffl W, Coccolini F, Di Saverio S, Kluger Y, Moore E, Catena F. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg. 2019;14:27. https://doi.org/10.1186/s13017-019-0247-0

Pimenta D, Dawood N. An unusual cause of pancreatitis in a 46-year-old returning traveller. BMJ Case Rep. 2015;2015:bcr2015210517. https://doi.org/10.1136/bcr-2015-210517

Phisalprapa P, Prachayakul V. Ascariasis as an unexpected cause of acute pancreatitis with cholangitis: a rare case report from urban area. JOP. 2013;14(1):88-91. https://doi.org/10.6092/1590-8577/1257

Husu HL, Valkonen MM, Leppäniemi AK, Mentula PJ. Occurrence and Risk Factors of Infected Pancreatic Necrosis in Intensive Care Unit-Treated Patients with Necrotizing Severe Acute Pancreatitis. J Gastrointest Surg. 2021;25(9):2289-2298. https://doi.org/10.1007/s11605-021-05033-x

Jiang X, Shi JY, Wang XY, Hu Y, Cui YF. The impacts of infectious complications on outcomes in acute pancreatitis: a retrospective study. Mil Med Res. 2020;7(1):38. https://doi.org/10.1186/s40779-020-00265-5

Dong X, Mao W, Ke L, Gao L, Zhou J, Ye B, Li G, Phillips A, Tong Z, Windsor J, Li W, Chinese Acute Pancreatitis Clinical Trials Group Capctg. The Diagnosis and Treatment of Local Complications of Acute Necrotizing Pancreatitis in China: A National Survey. Gastroenterol Res Pract. 2021;2021:6611149. https://doi.org/10.1155/2021/6611149

Keiser J, Utzinger J. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis. JAMA. 2008;299(16):1937-48. https://doi.org/10.1001/jama.299.16.1937

Moser W, Schindler C, Keiser J. Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis. BMJ. 2017;358:j4307. https://doi.org/10.1136/bmj.j4307

Chai JY, Sohn WM, Hong SJ, Jung BK, Hong S, Cho S, Park JB, Kim IS, Kim S, Lee KH, Jeoung HG, Htoon TT, Tin HH. Effect of Mass Drug Administration with a Single Dose of Albendazole on Ascaris lumbricoides and Trichuris trichiura Infection among Schoolchildren in Yangon Region, Myanmar. Korean J Parasitol. 2020;58(2):195-200. https://doi.org/10.3347/kjp.2020.58.2.195

Goldstein P. Loss of the central rachis and synaptonemal complexes during meiotic prophase in female Ascaris lumbricoides var. suum after exposure to albendazole. Journal of Helminthology. 2021;95(32):1-4. https://doi.org/10.1017/S0022149X21000225

Krücken J, Fraundorfer K, Mugisha JC, Ramünke S, Sifft KC, Geus D, Habarugira F, Ndoli J, Sendegeya A, Mukampunga C, Bayingana C, Aebischer T, Demeler J, Gahutu JB, Mockenhaupt FP, von Samson-Himmelstjerna G. Reduced efficacy of albendazole against Ascaris lumbricoides in Rwandan schoolchildren. Int J Parasitol Drugs Drug Resist. 2017;7(3):262-271. https://doi.org/10.1016/j.ijpddr.2017.06.001

Sanglas L, Aviles FX, Huber R, Gomis-Rüth FX, Arolas JL. Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite. Proc Natl Acad Sci U S A. 2009;106(6):1743-7. https://doi.org/10.1073/pnas.0812623106

Figura 1. Gusano de áscaris en la sonda nasogástrica.

Published

2021-10-01

How to Cite

Barbosa Valenzuela, S. C., Nieto del Río, M. L., Ramirez, D. ., Ariza Daza, J. ., Montañez Coronado, W., & Alvarado, L. . (2021). Necrotizing pancreatitis due to Ascaris lumbricoides: Causes, diagnosis, and current treatment. Revista Colombiana De Gastroenterología, 36(4), 514–518. https://doi.org/10.22516/25007440.671

Altmetric

Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views
QR Code