Rare Association of Budd-Chiari Syndrome with COVID-19: A Case Report

Authors

DOI:

https://doi.org/10.22516/25007440.920

Keywords:

Budd-Chiari Syndrome, Hepatic obstruction of venous outflow, Coronavirus infections

Abstract

Introduction: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a virus that can cause respiratory infections and pose a risk to patients’ lives. While it primarily affects the airways, it can also lead to extrapulmonary clinical manifestations, such as hypercoagulable states, resulting in conditions like cerebrovascular disease, acute myocardial infarction, and, in rare cases, Budd-Chiari syndrome.

Clinical case: This case involves a patient who was admitted to the emergency room with dyspnea on moderate exertion, progressive functional class deterioration, lower extremity edema, cough, fever, and weakness. The patient had a history of coronavirus disease 2019 (COVID-19) infection one month prior. Abdominal CT scan revealed subacute Budd-Chiari syndrome involving the middle sub-hepatic vein, along with right ventricle thrombosis, and a positive test for SARS-CoV-2.

Conclusions: Budd-Chiari syndrome has multiple causes, primarily associated with hypercoagulable states or the presence of neoplasms that disrupt liver function or obstruct hepatic venous drainage. However, the understanding of the relationship between COVID-19 hypercoagulability and Budd-Chiari syndrome is still limited. Further research is needed to explore the heterogeneity of its pathogenesis in the context of the SARS-CoV-2 pandemic.

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Author Biographies

Julio Cesar Velasco Castro, Universidad de Boyacá

Departamento de investigación, Hospital Regional de la Orinoquía. Yopal, Colombia. Médico interno, Universidad de Boyacá. Tunja, Colombia

Maria Paula Patarroyo, Hospital Regional de la Orinoquía

Médico interno, Universidad de Boyacá, Tunja, Colombia. Departamento de investigación, Yopal, Colombia.

Juan David Galan, Hospital Regional de la Orinoquía

Médico interno, Universidad Cooperativa. Villavicencio, Colombia. Departamento de investigación, Yopal, Colombia.

Lorena Garcia Agudelo, Hospital Regional de la Orinoquía

Médica epidemióloga, Hospital Regional de la Orinoquia. Yopal, Colombia

Ledmar Jovanny Vargas Rodriguez, Universidad de Boyacá

Departamento de investigación, Hospital Regional de la Orinoquía. Yopal, Colombia.

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Figure 1. Contrasted CT revealing: A. Right atrial thrombosis; B. BCS detected by the absence of blood flow at the level of the outflow tract of the middle suprahepatic vein, hepatomegaly; C and D. Splenomegaly, ascites, and collateral circulation. Courtesy of the radiology department, Hospital Regional de la Orinoquia (HORO).

Published

2023-06-22

How to Cite

Velasco Castro, J. C., Patarroyo, M. P., Galan, J. D., Garcia Agudelo, L., & Vargas Rodriguez, L. J. (2023). Rare Association of Budd-Chiari Syndrome with COVID-19: A Case Report. Revista Colombiana De Gastroenterología, 38(2), 194–198. https://doi.org/10.22516/25007440.920

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Case report

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