Compromiso gastrointestinal y hepático en Síndrome de Sjögren primario: reporte de caso y revisión de la literatura
DOI:
https://doi.org/10.22516/25007440.918Palabras clave:
Síndrome de Sjögren, Colangitis Esclerosante, Anomalías del Sistema Digestivo, Anticuerpos Antinucleares, Enfermedades GastrointestinalesResumen
El síndrome de Sjögren es una enfermedad autoinmune sistémica que se caracteriza por sequedad ocular y bucal por afección de glándulas exocrinas, sin embargo, puede manifestarse con síntomas gastrointestinales que abarcan un espectro amplio que van desde dismotilidad esofágica e intestinal, acalasia, hipoclorhidria, gastritis crónica atrófica, hasta enzimodeficiencia pancreática, disfunción biliar y cirrosis hepática, presentando variación en sus manifestaciones clínicas, y asociándose abordajes erróneos en muchas ocasiones. En este artículo se hace una revisión acerca de las manifestaciones gastrointestinales de síndrome de Sjögren, y se presenta el caso de una mujer en la octava década de la vida con síndrome de Sjögren, cursando de modo asintomático a nivel hepatobiliar, documentación de alteración en pruebas de perfil hepático, y diagnóstico ulterior de colangitis esclerosante primaria, recibiendo manejo inicial con ácido ursodesoxicólico y colangiopancreatografía retrograda con dilataciones endoscópicas. Esta asociación es infrecuente y justifica consideración especial.
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