Quality of Life and Sexual Function in Women with Liver Cirrhosis in Colombia

Authors

DOI:

https://doi.org/10.22516/25007440.1063

Keywords:

Quality of life, Women, Cirrhosis, Sexual health, Psychological sexual dysfunctions

Abstract

Introduction: The female sex has been systematically identified as one of the predictors of poor quality of life in patients with cirrhosis. However, the relationship between quality of life and sexual function in women with cirrhosis has not been widely studied.

Aim: To determine the relationship between quality of life and sexual function in women with cirrhosis.

Materials and methods: A cross-sectional observational study. Female patients aged 18 to 69 years were included. The SF-36-V2 survey assessed health-related quality of life, and the IFSF-6 evaluated sexual function. Univariate and multivariate linear regression was used to identify the relationship between quality of life and sexual function. Statistical significance was set at a p-value < 0.05.

Results: 36 patients were available for analysis. The average age was 61 years. In the SF36-V2 survey, the physical component summary mean was 58, and the mental component summary mean was 56. The IFSF-6 had an average of 10. Sexual dysfunction occurred in 80% of patients. The IFSF-6 score was positively related to health-related quality of life. Factors associated with the deterioration of sexual function were age and menopause. The Child-Pugh score and body mass index were the main determinants of health-related quality of life.

Conclusions: Sexual function could be a determinant of quality of life in women with cirrhosis.

Downloads

Download data is not yet available.

Author Biographies

Ismael de Jesús Yepes Barreto, Universidad de Cartagena

Doctorado, PhD. Profesor auxiliar, Universidad de Cartagena. Soluciones Integrales en Gastroenterología
y Hepatopatología SAS. Cartagena, Colombia.

Luis Arboleda-Rivero, Clínica Universitaria Medicina Integral

Especialista en medicina interna. Internista y docente. Universidad del Sinú. Montería, Córdoba, Colombia.

María Lwiggi Garcia Doria, Clínica Zayma

Médico general. Montería, Córdoba, Colombia.

References

The WHOQOL Group. The Development of the World Health Organization Quality of Life Assessment Instrument (the WHOQOL). En: Orley J, Kuyken W (editores). Quality of Life Assessment: International Perspectives. Springer Berlin Heidelberg; 1994. p. 41-57. https://doi.org/10.1007/978-3-642-79123-9_4

Urzúa MA. Calidad de vida relacionada con la salud: elementos conceptuales. Rev Med Chil. 2010;138(3):358-65. https://doi.org/10.4067/S0034-98872010000300017

Loria A, Escheik C, Gerber NL, Younossi ZM. Quality of life in cirrhosis. Curr Gastroenterol Rep. 2013;15(1):301. https://doi.org/10.1007/s11894-012-0301-5

North CS, Devereaux R, Pollio DE, Hong BA, Jain MK. Patient perspectives on hepatitis C and its treatment. Eur J Gastroenterol Hepatol. 2014;26(1):74-81. https://doi.org/10.1097/MEG.0b013e32836382b5

Orr JG, Homer T, Ternent L, Newton J, McNeil CJ, Hudson M, et al. Health related quality of life in people with advanced chronic liver disease. J Hepatol. 2014;61(5):1158-65. https://doi.org/10.1016/j.jhep.2014.06.034

Afendy A, Kallman JB, Stepanova M, Younoszai Z, Aquino RD, Bianchi G, et al. Predictors of health-related quality of life in patients with chronic liver disease. Aliment Pharmacol Ther. 2009;30(5):469-76. https://doi.org/10.1111/j.1365-2036.2009.04061.x

Mejía G, Gómez MT, Moreno-Medina K. Evaluación de la calidad de vida relacionada con la salud pre y post trasplante hepático, en pacientes de un hospital de alta complejidad. Psychologia. 2019;13(1):65-72. https://doi.org/10.21500/19002386.3721

Hamer J, McDonald R, Zhang L, Verma S, Leahey A, Ecclestone C, et al. Quality of life (QOL) and symptom burden (SB) in patients with breast cancer. Support Care Cancer. 2017;25(2):409-19. https://doi.org/10.1007/s00520-016-3417-6

Amodio P, Salari L, Montagnese S, Schiff S, Neri D, Bianco T, et al. Hepatitis C virus infection and health-related quality of life. World J Gastroenterol. 2012;18(19):2295-9. https://doi.org/10.3748/wjg.v18.i19.2295

Neong SF, Billington EO, Congly SE. Sexual Dysfunction and Sex Hormone Abnormalities in Patients With Cirrhosis: Review of Pathogenesis and Management. Hepatology. 2019;69(6):2683-95. https://doi.org/10.1002/hep.30359

Blümel JE, Binfa EL, Cataldo AP, Carrasco VA, Izaguirre LH, Sarrá CS. Índice de función sexual femenina: un test para evaluar la sexualidad de la mujer. Rev Chil Obstet Ginecol. 2004;69(2):118-25. https://doi.org/10.4067/S0717-75262004000200006

Faubion SS, Rullo JE. Sexual dysfunction in women: A practical approach. Am Fam Physician. 2015;92(4):281-8.

Fliegner M, Richter-Appelt H, Krupp K, Brunner F. Sexual Function and Socio-Sexual Difficulties in Women with Polycystic Ovary Syndrome (PCOS). Geburtshilfe Frauenheilkd. 2019;79(5):498-509. https://doi.org/10.1055/a-0828-7901

Pozzo MJ, Mociulsky J, Martinez ET, Senatore G, Farias JM, Sapetti A, et al. Diabetes and Quality of Life: Initial Approach to Depression, Physical Activity, and Sexual Dysfunction. Am J Ther. 2016;23(1):e159-71. https://doi.org/10.1097/01.mjt.0000433949.24277.19

Chang SR, Yang CF, Chen KH. Relationships between body image, sexual dysfunction, and health-related quality of life among middle-aged women: A cross-sectional study. Maturitas. 2019;126:45-50. https://doi.org/10.1016/j.maturitas.2019.04.218

Abozead SE, Abdelrahman G, Hassan A, Ibrahim WH. Sexual Dysfunction and Health Related Quality of Life among Female Patients Undergoing Hemodialysis. American Journal of Nursing Research. 2018;6(6):547-52. https://doi.org/10.12691/ajnr-6-6-24

Sun V, Grant M, Wendel CS, McMullen CK, Bulkley JE, Herrinton LJ, et al. Sexual Function and Health-Related Quality of Life in Long-Term Rectal Cancer Survivors. J Sex Med. 2016;13(7):1071-9. https://doi.org/10.1016/j.jsxm.2016.05.005

Yepes Barreto I, Lepesqueur Guillen L, Cadavid Asis S. Predictores de calidad de vida en pacientes con enfermedad hepática crónica en Colombia. Rev Col Gastroenterol. 2015;30(4):390-8. https://doi.org/10.22516/25007440.2

Yepes Barreto IDJ, Meza ZC, Contreras MNM. Calidad de vida en pacientes con hepatitis C crónica en Colombia. Rev Col Gastroenterol. 2017;32(2):112-9. https://doi.org/10.22516/25007440.139

Vilagut G, Ferrer M, Rajmil L, Rebollo P, Permanyer M, Quintana JM. et al. El Cuestionario de Salud SF-36 español: una década de experiencia y nuevos desarrollos. Gac Sanit. 2005;19(2):135-150. https://doi.org/10.1157/13074369

Alonso J, Ferrer M, Gandek B, Ware JE Jr, Aaronson NK, Mosconi P, et al. Health-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project. Qual Life Res. 2004;13(2):283-298. https://doi.org/10.1023/B:QURE.0000018472.46236.05

Isidori AM, Pozza C, Esposito K, Giugliano D, Morano S, Vignozzi L, et al. Development and validation of a 6-item version of the female sexual function index (FSFI) as a diagnostic tool for female sexual dysfunction. J Sex Med. 2010;7(3):1139-46. https://doi.org/10.1111/j.1743-6109.2009.01635.x

Bae H, Park H. Sexual function, depression, and quality of life in patients with cervical cancer. Support Care Cancer. 2016;24(3):1277-83. https://doi.org/10.1007/s00520-015-2918-z

Aslan E, Beji NK, Gungor I, Kadioglu A, Dikencik BK. Prevalence and risk factors for low sexual function in women: a study of 1,009 women in an outpatient clinic of a university hospital in Istanbul. J Sex Med. 2008;5(9):2044-52. https://doi.org/10.1111/j.1743-6109.2008.00873.x

Nazarpour S, Simbar M, Ramezani Tehrani F, Alavi Majd H. Quality of life and sexual function in postmenopausal women. J Women Aging. 2018;30(4):299-309. https://doi.org/10.1080/08952841.2017.1395539

Kılıç M. Prevalence and risk factors of sexual dysfunction in healthy women in Turkey. Afr Health Sci. 2019;19(3):2623-33. https://doi.org/10.4314/ahs.v19i3.38

Elshimi E, Morad W, Mohamad NE, Shebl N, Waked I. Female Sexual Dysfunction Among Egyptian Patients with Chronic Hepatitis C. J Sex Med. 2014;11(3):768-75. https://doi.org/10.1111/jsm.12412

Bach N, Schaffner F, Kapelman B. Sexual behavior in women with nonalcoholic liver disease. Hepatology. 1989;9(5):698-703. https://doi.org/10.1002/hep.1840090507

Thiele M, Askgaard G, Timm HB, Hamberg O, Gluud LL. Predictors of health-related quality of life in outpatients with cirrhosis: results from a prospective cohort. Hepat Res Treat. 2013;2013:479639. https://doi.org/10.1155/2013/479639

Apple R, Samuels LR, Fonnesbeck C. Body mass index and health‐related quality of life. Obes Sci Pract. 2018;4(5):417-426. https://doi.org/10.1002/osp4.292

Poggiogalle E, Di Lazzaro l, Pinto A. Health-related quality of life and quality of sexual life in obese subjects. Int J Endocrinol. 2014;2014:847871. https://doi.org/10.1155/2014/847871

Morotti E, Battaglia B. Body mass index, stunkard figure rating scale, and sexuality in young italian women: a pilot study. J Sexual Med. 2013;10(4):1034-1043. https://doi.org/10.1111/jsm.12045

Vallejo-Medina P, Pérez-Durán C, Saavedra-Roa A. Translation, Adaptation, and Preliminary Validation of the Female Sexual Function Index into Spanish (Colombia). Arch Sex Behav. 2018;47(3):797-810. https://doi.org/10.1007/s10508-017-0976-7

Figura 1. Diagrama de flujo selección de pacientes. Figura elaborada por los autores.

Published

2023-12-19

How to Cite

Yepes Barreto, I. de J., Arboleda Rivero, L. A., & Garcia Doria, M. L. (2023). Quality of Life and Sexual Function in Women with Liver Cirrhosis in Colombia. Revista Colombiana De Gastroenterología, 38(4), 439–447. https://doi.org/10.22516/25007440.1063

Issue

Section

Originals articles

Altmetric

Crossref Cited-by logo
Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views
QR Code

Some similar items: