Liver Biopsy in Children Under 5 Years Experience in a Colombian Pediatric Hospital
DOI:
https://doi.org/10.22516/25007440.21Keywords:
Liver biopsy, pediatric liver disease, cholestasisAbstract
Objective: The objective of this study was to evaluate the frequency and distribution of liver diseases justifying liver biopsies in Colombian pediatric patients.
Methodology: Liver biopsies performed at a pediatric hospital over a period of 5 years were assessed and then sorted according to age groups and diagnoses.
Results: A total of 182 histopathological studies of 168 patients (14 of whom had two procedures each.) were found: 53.6% were boys, and 46.4% were girls. Young infants were the age group which had the most
biopsies, and cholestasis was the most frequent reason for these iopsies. Other diseases diagnosed included inflammatory processes (30.2%), abnormalities of the biliary tract (26.4%), tumor diseases (14.9%) and
metabolic/storage disorders (9.3%). The remaining percentages were for rare entities and normal biopsies.
Conclusion: Liver biopsies are useful and practical for the diagnosis of pediatric liver disease when combined with clinical and laboratory data. In our study, inflammatory processes, abnormalities of the biliary tract
and tumor diseases were the most frequently diagnosed categories
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