Simultaneous appearance of early gastric cancer and GIST

Authors

  • Martín Alonso Gómez Zuleta Universidad Nacional de Colombia
  • Javier Humberto Riveros Vega Pontificia Universidad Javeriana, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia.
  • Oscar Fernando Ruíz Morales Universidad San Martín, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia

DOI:

https://doi.org/10.22516/25007440.398

Keywords:

Hematemesis, manes, gastric cancer, gastrointestinal stromal tumor, GIST, synchronous tumor, ki 67, surgery, endoscopic ultrasound, submucosal dissection, gastrectomy

Abstract

We present the case of a 74-year-old male patient who was admitted with symptoms of upper digestive bleeding. Endoscopy of his upper digestive tract found an ulcerated lesion and a subepithelial lesion in his stomach. Complete studies including gastric endoscopic ultrasound showed a mucosal lesion infiltrating the submucosa which was suggestive of early gastric cancer as well as a subepithelial lesion on the muscle that was suggestive of a gastrointestinal stromal tumor (GIST). Staging showed no metastatic compromise, so surgery was performed, and histology subsequently confirmed the findings.

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Author Biographies

Martín Alonso Gómez Zuleta, Universidad Nacional de Colombia

Especialista en Gastroenterología, Universidad Nacional de Colombia, Especialista en Medicina Interna, Universidad Nacional de Colombia, Hospital Universitario Nacional, Hospital Occidente de Kennedy, Unidad de gastroenterología y Ecoendoscopia-UGEC. Bogotá, Colombia

Javier Humberto Riveros Vega, Pontificia Universidad Javeriana, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia.

Especialista en Gastroenterología, Universidad Nacional de Colombia, Especialista en Medicina Interna, Pontificia Universidad Javeriana, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia. Bogotá, Colombia

Oscar Fernando Ruíz Morales, Universidad San Martín, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia

Especialista en Gastroenterología, Universidad Nacional de Colombia, Especialista en Medicina Interna, Universidad San Martín, Hospital Occidente de Kennedy, Hospital Universitario Nacional de Colombia. Bogotá, Colombia

References

Ferlay J, Shin H, Bray F, Formar D, Mathers C, Parkin D. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893-917. https://doi.org/10.1002/ijc.25516.

Bowrey DJ, Griffin SM, Wayman J, Karat D, Hayes N, Raimes SA. Use of alarm symptoms to select dyspeptics for endoscopy causes patients with curable esophagogastric cancer to be overlooked. Surg Endosc. 2006;20(11):1725-8. https://doi.org/10.1007/s00464-005-0679-3.

Kwee R, Kwee T. Imaging in local staging of gastric cancer: a systematic review. J Clin Oncol. 2007;25(15):2107-16. https://doi.org/10.1200/JCO.2006.09.5224.

Tatsuta M, Iishi H, Okuda S, Oshima A, Taniguchi H. Prospective evaluation of diagnostic accuracy of gastrofiberscopic biopsy in diagnosis of gastric cancer. Cancer. 1989;63(7):1415-20.

Japanese Gastric Cancer Association. Japanese Classification of Gastric Carcinoma - 2nd English Edition. Gastric cancer. 1998;1(1):10-24. https://doi.org/10.1007/PL00011681.

Sanchez-Hidalgo JM, Duran-Martinez M, Molero-Payan R, Rufian-Peña S, Arjona-Sanchez A, Casado-Adam A, et al. Gastrointestinal stromal tumors: A multidisciplinary challenge. World J Gastroenterol. 2018;24(18):1925-41. https://doi.org/10.3748/wjg.v24.i18.1925.

Harlan LC, Eisenstein J, Russell MC, Stevens JL, Cardona K. Gastrointestinal stromal tumors: treatment patterns of a populationbased sample. J Surg Oncol. 2015;111(6):702-7. https://doi.org/10.1002/jso.23879.

Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002; 33: 459-65. https://doi.org/10.1053/hupa.2002.123545.

Tio TL, Tytgat GN, den Hartog Jager FC. Endoscopic ultrasonography for the evaluation of smooth muscle tumors in the upper gastrointestinal tract: an experience with 42 cases. Gastrointest Endosc. 1990;36(4):342-50.

Ando N, Goto H, Niwa Y, Hirooka Y, Ohmiya N, Nagasaka T, et al. The diagnosis of GI stromal tumors with EUSguided fine needle aspiration with immunohistochemical analysis. Gastrointest Endosc. 2002;55(1):37-43. https://doi.org/10.1067/mge.2002.120323.

Everett M, Gutman H. Surgical management of gastrointestinal stromal tumors: analysis of outcome with respect to surgical margins and technique. J Surg Oncol 2008; 98: 588-593. https://doi.org/10.1002/jso.21030.

Dematteo RP, Gold JS, Saran L, Gönen M, Liau KH, Maki RG, et al. Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST). Cancer 2008;112(3):608-15. https://doi.org/10.1002/cncr.23199.

Gold JS, Dematteo RP. Combined surgical and molecular therapy: the gastrointestinal stromal tumor model. Ann Surg. 2006;244(2):176-84. https://doi.org/10.1097/01.sla.0000218080.94145.cf.

Novitsky YW, Kercher KW, Sing RF, Heniford BT. Long-term outcomes of laparoscopic resection of gastric gastrointestinal estromal tumors. Ann Surg 2006;243(6):738-45. https://doi.org/10.1097/01.sla.0000219739.11758.27.

Bischof DA, Kim Y, Dodson R, Carolina Jimenez M, Behman R, Cocieru A, et al. Open versus minimally invasive resection of gastric GIST: a multiinstitutional analysis of short- and long-term outcomes. Ann Surg Oncol. 2014;21(9):2941-8. https://doi.org/10.1245/s10434-014-3733-3.

Balde AI, Chen T, Hu Y, Redondo N JD, Liu H, Gong W, et al. Safety analysis of laparoscopic endoscopic cooperative surgery versus endoscopic submucosal dissection for selected gastric gastrointestinal stromal tumors: a propensity scorematched study. Surg Endosc. 2017;31(2):843-51. https://doi.org/10.1007/s00464-016-5042-3.

Kramer K, Wolf S, Mayer B, Schmidt SA, Agaimy A, Henne-Bruns D, et al. Frequence, spectrum and prognostic impact of additional malignancies in patients with gastrointestinal stromal tumors. Neoplasia. 2015 Jan;17(1):134-40. https://doi.org/10.1016/j.neo.2014.12.001.

Gonçalves R, Linhares E, Albagli R, Valadao M, Vilhena B, Romano S, et al. Occurrence of other tumors in patients with GIST. Surg Oncol. 2010;19(4):140-3. https://doi.org/10.1016/j.suronc.2010.06.004.

Wronski M, Ziarkiewicz-Wroblewska B, Gornicka B, Cebulski W, Slodkowski M, Wasiutynski A, et al. Synchronous occurrence of gastrointes- tinal stromal tumors and other primary gastrointestinal neoplasms. World J Gastroenterol. 2006;12(33):5360. https://doi.org/10.3748/wjg.v12.i33.5360.

Published

2019-07-02

How to Cite

Gómez Zuleta, M. A., Riveros Vega, J. H., & Ruíz Morales, O. F. (2019). Simultaneous appearance of early gastric cancer and GIST. Revista Colombiana De Gastroenterología, 34(2), 197–201. https://doi.org/10.22516/25007440.398

Issue

Section

Case report

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