Risk factors for gastric cancer. What is their role?
DOI:
https://doi.org/10.22516/25007440.656Keywords:
Gastric cancer, Risk factors, Prevention, High-risk groupsAbstract
The process of gastric carcinogenesis is multifactorial and sequential. We do not fully understand this, but
we know the natural history of the disease described by Dr. Pelayo Correa and the existence of multiple risk
factors. Identifying the factors involved in each step and managing them appropriately could help reduce the
incidence of gastric cancer (GC). Helicobacter pylori (HP) infection is probably the most widely known and
discussed risk factor. However, there are other factors such as lifestyle, type of diet, family history of cancer,
among others, that are also involved in the development and incidence of this cancer and have a wide window of time to exert their influence.
At the population level, identification and awareness of these risk factors can provide insight into the etiology
of the disease and are essential for planning, monitoring and evaluating prevention plans, policies and
strategies. It is therefore necessary to develop a study tool based on risk factor identification that can be added to endoscopic and histological findings and used in clinical practice for GC risk classification.
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