Síntomas gastrointestinales en la enfermedad por COVID-19 y sus implicaciones en enfermedad inflamatoria intestinal

  • Viviana Parra Clinica Palermo - Gastroadvanced IPS
  • Cristian Flórez Clinica Palermo - Gastroadvanced IPS
  • Consuelo Romero Universidad del Bosque
  • Fernando García del Risco Universidad de Cartagena
Palabras clave: SARS virus, enfermedad inflamatoria intestinal, covid 19, inmunosupresión, heces, tracto gastrointestinal

Resumen

La pandemia por SARS-Cov-2, ha tomado gran relevancia por su impacto en los diversos sistemas de salud en el mundo. Inicialmente solo se contemplaba la importancia de los síntomas respiratorios y la fiebre; sin embargo, a diario tenemos más reportes y publicaciones sobre la relevancia que está teniendo en el sistema digestivo, ya que algunos pacientes informan síntomas gastrointestinales como diarrea, vómito y dolor abdominal. Los estudios han identificado el ARN del SARS-CoV-2 en muestras de heces de pacientes infectados, en las que se encontró que su receptor que es el de la enzima convertidora de angiotensina 2 (ECA2) se expresaba altamente en las células epiteliales gastrointestinales. Esto sugiere que el SARS-CoV-2 puede infectar activamente y replicarse en el tracto gastrointestinal. Esto tiene implicaciones importantes para el tratamiento de la enfermedad, la transmisión y el control de infecciones. En pacientes con patologías crónicas como la enfermedad inflamatoria intestinal (EII), se han generado gran cantidad de preguntas e incertidumbres ante la presencia de COVID-19 junto con las implicaciones que pueden tener tanto en la severidad de los síntomas, como en la descompensación de la patología de base y en la continuidad del tratamiento inmunosupresor.

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Biografía del autor/a

Viviana Parra, Clinica Palermo - Gastroadvanced IPS

Medicina Interna, Reumatología, Gastroenterología y Endoscopia Digestiva, Clínica Palermo - Gastroadvanced IPS, Universidad El Bosque. Bogotá, Colombia.

Cristian Flórez, Clinica Palermo - Gastroadvanced IPS

Medicina Interna, Gastroenterología y Endoscopia Digestiva, Clinica Palermo - Gastroadvanced IPS, Fundación Valle del Lili, Universidad El Bosque. Bogotá, Colombia

Consuelo Romero, Universidad del Bosque

Doctor en ciencias Biológicas, Profesora Universidad del Bosque

Fernando García del Risco, Universidad de Cartagena

Gastroenterólogo endoscopista, profesor titular de Gastroenterología, Universidad de Cartagena, presidente de la Asociación Colombiana de Gastroenterología. Cartagena, Colombia.

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Publicado
2020-05-06
Cómo citar
Parra Izquierdo, V., Flórez Sarmiento, C. F., Romero-Sánchez, M. C., & García del Risco, F. (2020). Síntomas gastrointestinales en la enfermedad por COVID-19 y sus implicaciones en enfermedad inflamatoria intestinal. Revista Colombiana De Gastroenterología, 35(Supl. 1), 45-55. https://doi.org/10.22516/25007440.532